The Arizona Cardinals have been underdogs in every game they have played this season so far. They were 12.5-point underdogs last week at home against the Dallas Cowboys. This week, they are on the road for their first divisional game of the season and are overwhelming underdogs. They take on the unbeaten San Francisco 49ers Sunday afternoon. Kickoff is at 4:25 p.m. ET at Levis Stadium in Santa Clara and the game will air on FOX.
Let’s take a look at the betting odds and lines for the Cardinals vs. 49ers Week 4 matchups from BetMGM.
The Cardinals picked up their first win of the season last week, beating Dallas 28-16 as 12.5-point home underdogs. They rushed for 222 yards as a team and held the Cowboys to one touchdown in five red-zone trips. They are 1-2.
The 49ers were 10.5-point home favorites last week on Thursday but beat the New York Giants 30-12. They are 3-0.
Cardinals at 49ers Week 4 odds and lines
Moneyline
- Cardinals +625 (bet $100 to win $625)
- 49ers -1000 (best $1,000 to win $100)
At +625, the Cardinals have only 13.79% implied odds of winning this game. If you bet them to win and they pull off the extremely unexpected upset, you win more than six times your wager.
At -1000, the Niners have 90.91% implied odds. Basically, the 49ers are more than 75% more likely to win than the Cardinals.
No, you shouldn’t bet the 49ers on the moneyline.
The Cardinals are 1-2 straight up while the Niners are 3-0.
Against the spread (ATS)
- Cardinals +14 (-110)
- 49ers -14 (-110)
This is a massive spread. The Cardinals are 3-0 ATS this season. The Niners are 2-1 ATS, failing to cover the 8.5-point spread in Week 2 with a seven-point win over the Rams.
The 14-point spread for this game is the largest one in the NFL in Week 4.
A $110 ATS wager on the Cardinals wins $100 if they win the game, finish with a tie or lose by 13 points or fewer.
A $110 ATS bet on the Niners wins $100 if they win by 15 points or more.
Total (Over/Under)
- Over 44 (-110)
- Under 44 (-110)
If the game has 45 combined points or more, a $110 bet on the Over wins $100.
A $110 bet on the Under wins $100 if they combine for no more than 43.
The Cardinals have had two games hit the Over.
Two of the Niners’ three games this season have stayed Under the projected total.
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