The Arizona Cardinals’ 2022 regular season schedule is out. They begin the season at home against the Kansas City Chiefs and will play four prime-time games. All are home games, although one is a “home” game in Mexico City.
It is the fourth season with Kliff Kingsbury as head coach and with Kyler Murray at quarterback.
They have improved their win totals each of the last three seasons and went 11-6 in 2021, making it to the playoffs for the first time since 2015. This year, they expect more.
They will play the first six games of the season without receiver DeAndre Hopkins, who was suspended after testing positive for a banned performance-enhancing substance.
They will play their final two games of the season on the road, closing out the year against the San Francisco 49ers.
The full schedule is below.
| Week | Date | Opponent | Time (AZ) | ||
| 1 | Sept. 11 | vs. | Kansas City Chiefs | 1:25 p.m. | Tickets |
| 2 | Sept. 18 | at | Las Vegas Raiders | 1:25 p.m. | Tickets |
| 3 | Sept. 25 | vs. | Los Angeles Rams | 1:25 p.m. | Tickets |
| 4 | Oct. 2 | at | Carolina Panthers | 1:05 p.m. | Tickets |
| 5 | Oct. 9 | vs. | Philadelphia Eagles | 1:25 p.m. | Tickets |
| 6 | Oct. 16 | at | Seattle Seahawks | 1:05 p.m. | Tickets |
| 7 | Oct. 20 (Thursday night) | vs. | New Orleans Saints | 5:15 p.m. | Tickets |
| 8 | Oct. 30 | at | Minnesota Vikings | 10 a.m. | Tickets |
| 9 | Nov. 6 | vs. | Seattle Seahawks | 1:05 p.m. | Tickets |
| 10 | Nov. 13 | at | Los Angeles Rams | 2:25 p.m. | Tickets |
| 11 | Nov. 21 (Monday night) | vs. | San Francisco 49ers (in Mexico City) | 5:15 p.m. | Tickets |
| 12 | Nov. 27 | vs. | Los Angeles Chargers | 2:05 p.m. | Tickets |
| 13 | Dec. 4 | BYE WEEK | |||
| 14 | Dec. 12 (Monday night) | vs. | New England Patriots | 6:15 p.m. | Tickets |
| 15 | Dec. 18 | at | Denver Broncos | 2:05 p.m. | Tickets |
| 16 | Dec. 25 (Sunday night) | vs. | Tampa Bay Buccaneers | 6:20 p.m. | Tickets |
| 17 | Jan. 1 | at | Atlanta Falcons | 11 a.m. | Tickets |
| 18 | Jan. 8 | at | San Francisco 49ers | TBD | Tickets |
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